Dr. Linda Yan, M.D. spent 10 years living and working as a physician in Philadelphia and now practices General Gastroenterology in the Hazleton area, treating a wide range of general digestive diseases and conditions. She takes great care in pursuing excellent outcomes while implementing up-to-date medicine to improve quality of life. Above all, Dr. Yan is focused on treating her patients with compassion and respect, keeping them at the center of their health care decisions.
Areas of expertise include: colonoscopy, upper endoscopy, small bowel endoscopy, capsule endoscopy, colon cancer screening, anemia, gastrointestinal bleeding, hemorrhoids, constipation, diarrhea, abdominal pain, heartburn and acid reflux, nausea, vomiting, bloating, celiac disease, gastrointestinal motility disorders, pancreas and bile duct disorders, liver disease, inflammatory bowel disease, and other conditions within the field of gastroenterology and hepatology.
Education and Training
Medical School
Jefferson Medical College (Sidney Kimmel Medical College at Thomas Jefferson University)
Internal Medicine Residency
Thomas Jefferson University Hospital
Gastroenterology & Hepatology Fellowship
Thomas Jefferson University Hospital
Awards/Honors
Outstanding Poster Presentation Award at the Cleveland Clinic Lerner Research Institute Retreat
American Heart Association Undergraduate Research Fellowship
DAAD RISE Scholarship (German Academic Exchange Research Internship)
Thomas Jefferson University Levine Research Scholarship at Jefferson Medical College
American Association for the Study of Liver Diseases Fall 2016 Emerging Liver Scholars Award Program and Ambassador
Graduated Summa Cum Laude in Premedicine from The Pennsylvania State University
Research Publications
Review Articles
Yoo J, Yan LH, Siddiqui AA. (2017) Can contrast harmonic endoscopic ultrasonography replace endoscopic ultrasonography-guided fine-needle aspiration in patients with solid pancreatic lesions? An American perspective. Endosc Ultrasound. 6(1): 1-3.
Yoo J, Kistler CA, Yan L, Dargan A, Siddiqui AA. (2016) Endoscopic ultrasound in pancreatic cancer: innovative applications beyond the basics. J Gastrointest Oncol. 7(6): 1019-1029.
Cosgrove ND, Yan L, Siddiqui A. (2015) Preoperative endoscopic ultrasound-guided fine needle aspiration for diagnosis of pancreatic cancer in potentially resectable patients: Is this safe? Endosc Ultrasound. 4(2); 81-84.
Manuscripts
Yan L, Dargan A, Nieto J, Shariaha RZ, Binmoeller KF, Adler DG, DeSimone M, Berzin T, Swahney M, Draganov PV, Yang DJ, Diehl DL, Wang L, Ghulab A, Butt N, Siddiqui AA. (2018) Direct endoscopic necrosectomy at the time of transmural stent placement results in earlier resolution of complex walled-off pancreatic necrosis: results from a large multicenter U.S. trial. Endosc Ultrasound. 8(3):172-179.
Yoo J, Yan L, Hasan R, Somalya S, Nieto J, Siddiqui AA. (2017) Feasibility, safety, and outcomes of a single-step endoscopic ultrasonography-guided drainage of pancreatic fluid collections without fluoroscopy using a novel electrocautery-enhanced lumen-apposing, self-expanding metal stent. Endosc Ultrasound. 6(2): 131-135.
Siddiqui A, Cosgrove N, Yan LH, Brandt D, Janowski R, Kalra A, Zhan T, Baron TH, Repici A, Taylor LJ, Adler DG. (2017) Long-term outcomes of palliative colonic stenting versus emergency surgery for acute proximal malignant colonic obstruction: a multicenter trial. Endosc Int Open. 5(1): E232-E238.
Yan L, Siddiqui AA, Laique SN, Saumoy M, Kahaleh M, Yoo J, Kalra A, Mathew A, Sterling J, Rao R, Lieberman M, Cosgrove N, Sharaiha RZ. (2017) A large multicenter study of recurrence after surgical resection of branch-duct intraductal papillary mucinous neoplasm of the pancreas. Minerva Gastroenterol Dietol. 63(1): 50-54.
Siddiqui AA, Adler DG, Nieto J, Shah JN, Binmoeller KF, Kane S, Yan L, Laique SN, Kowalski T, Loren DE, Taylor LJ, Munigala S, Bhat YM. (2016) EUS-guided drainage of peripancreatic fluid collections and necrosis by using a novel lumen-apposing stent: a large retrospective, multicenter U.S. experience (with videos). Gastrointest Endosc. 83(4): 699-707.
Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. (2015) Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response. Biochem J. 471(1): 37-51.
Huang C, Huang B, Bi F, Yan LH, Tong J, Huang J, Xia XG, Zhou H. (2014) Profiling the genes affected by pathogenic TDP-43 in astrocytes. J Neurochem. 129(6):932-9.
Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C. (2014) Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation. J Neurochem. 129(1):99-106.
Ithychanda SS, Hsu D, Li H, Yan L, Liu D, Das M, Plow EF, Qin J (2009) Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk. J. Biol. Chem. 284(50):35113-21.
Abstracts/Posters
Duffey K, Chapin S, Yan L, Moleski S. “The Benefits of Time Spent in Nature on Symptoms and Quality of Life Among Patients With IBS.” American College of Gastroenterology 2020 Annual Scientific Meeting.
Yan L, Gueorguieva I, Stickler M, Choudhary C, Moleski S. “Irritiable Bowel Syndrome (IBS) Symptoms and Hormonal Contraception, Is There A Relationship?” Digestive Diseases Week 2020 and the 2020 North American Conference of Gastroenterology Fellows.
Saumoy M, Siddiqui AA, Yan LH, Kaplan JH, Yalamanchili S, Khalid A, Tyberg A, Soomro A, Mazhar SM, Gaidhane M, Lieberman M, Hoda R, Rao R, Kahaleh M, Sharaiha RZ. (2016) A Novel Algorithm for the Prediction of Malignancy in Patients Undergoing EUS-FNA of Pancreatic Cystic Lesions. Gastroenterology.
Saumoy M, Siddiqui AA, Yan LH, Kaplan JH, Yalamanchili S, Khalid A, Tyberg A, Soomro A, Mazhar SM, Gaidhane M, Lieberman M, Hoda R, Rao R, Kahaleh M, Sharaiha RZ. “A Novel Algorithm for the Prediction of Malignancy in Patients Undergoing EUS-FNA of Pancreatic Cystic Lesions.” Digestive Disease Week on May 22, 2016.
Siddiqui AA, Adler DG, Nieto J, Shah JN, Binmoeller K, Kane SD, Yan LH, Laique SN, Kowalski T, Loren D, Bhat YM. “EUS Guided Drainage of Peripancreatic Fluid Collections and Necroses using a Novel Lumen-Apposing Stent: a Large Multicenter U.S. Experience.” Digestive Disease Week on May 17, 2015.
Kistler CA, Henry C, Yan L, Jiang W, Kozuch P. “Microscopic Gastritis: A Case Series Highlighting the Diagnostic and Therapeutic Challenges.” American College of Gastroenterology 2014 Annual Scientific Meeting on October 19, 2014
Chan TO, Zhang J, Tiegs BC, Yan L, Blumhof B, Keny N, Penny M, Li X, Armen RS, Pascal JM, Rodeck U, Penn RB. (2014) C-Terminal Modifications of Akt Kinase Boost Cellular Responses to Insulin by Inhibiting Activation Loop Dephosphorylation. Circulation.
Yan L, O-Chi J, Zhang J, Chan TO. “Differential Activation of Akt1 and Akt2 Protein Kinases in Myoblasts.” Sigma Xi Student Research Day on April 17, 2013
Yan L, Steinl C, Klein G. “The Influence of Hypoxia in the Stem Cell Niche on Cell-Matrix and Cell-Cell Interactions.” University of Heidelberg on July 22, 2011
Ithychanda SS, Hsu D, Li H, Yan L, Liu D, Das M, Plow EF, Qin J (2010) Filamin Assembles Integrin Prior to Activation: A Hypothesis. Arterioscler Thromb Vasc Biol. 30(11): 189
Yan L, Ithychanda S, Hsu D, Li H, Liu D, Qin J. “Integrin Binds Many Filamin Repeats: The Odd Case of Repeat 23.” Cleveland Clinic Lerner Research Institute Retreat on September 8, 2008.
Quality Improvement
Laothamatas K, Yan L, Kramer D, Enriquez M, Lee A. “Improving Pneumococcal Vaccination Rates in Jefferson Hospital Ambulatory Practice Patients.” Jefferson House Staff Quality Improvement and Patient Safety Conference on June 1, 2017